PC version Fans have made a PC version. Some are still early, so read the project page first.
Fans took Destroy All Humans! apart and rebuilt it so it runs natively on a computer, often with widescreen, higher frame rates and mods. Here is the project we know about:
This is a vibe coded Destroy All Humans Static Recompilation, yeah I know it might bum some people out but nobody is gonna do and I at least want to make sure this is as accurate as humanly possible and as mod friendly as possible.