PC version Fans have made a PC version. Some are still early, so read the project page first.
Fans took MLB Power Pros 2008 apart and rebuilt it so it runs natively on a computer, often with widescreen, higher frame rates and mods. Here is the project we know about:
Native recompilation of MLB Power Pros 2008 (Wii) on Wiicompiled. No game data included.