PC version Fans have made a PC version. Some are still early, so read the project page first.
Fans took Serious Sam: Next Encounter apart and rebuilt it so it runs natively on a computer, often with widescreen, higher frame rates and mods. Here is the project we know about:
This is an Unofficial PC port of Serious Sam: Next Encounter (GameCube, 2004), made by recompiling the game's code to native x64. Your own legally acquired Rev 1 US rom or PAL rom is required; the game is built on your PC and no game code i