PC version Fans have made a PC version. Some are still early, so read the project page first.
Fans took Tiny Toon Adventures: Buster's Hidden Treasure apart and rebuilt it so it runs natively on a computer, often with widescreen, higher frame rates and mods. Here is the project we know about:
A native PC port of Tiny Toon Adventures: Buster's Hidden Treasure (Sega Mega Drive / Genesis). Widescreen, save states, filters, and an in-game menu. Bring your own US ROM.